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‎"WEINBERG, MICHEL et P. SÉGUIN - ISOLATION OF CLOSTRIDIUM HISTOLYTICUM.‎

Reference : 59100

(1916)

‎Contribution à l'étiologie de la gangrène gazeuse.‎

‎(Paris, Gauthier-Villars), 1916. 4to. No wrappers. In: ""Comptes Rendus Hebdomadaires des Séances de L'Academie des Sciences"", Tome 163, No 17. Pp. (405-) 452. (Entire issue offered). The paper: pp. 449--51.‎


‎First printing of the paper in which the authors announced the isolation of Cl. histolyticum.""In 1916, Weinberg and Séguin isolated this bacterium from patients with gas gangrene and called it Bacillus histolyticus. They discovered this bacterium was pathogenic for guinea pigs, mice, and rabbits, but less so for rats. Intramuscular injection of culture caused extensive local tissue destruction, extrusion of a hemorrhagic muscle pulp, splitting of the skin, denudation of the bone, and sometimes autoamputation. In 1922, Heller renamed the bacterium Weinbergillus histolyticus, and a year later Bergey, Harrison, et al. reclassified it as Clostridium histolyticum."" (Wikipedia).Garrison & Morton, 2551.‎

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