(Paris, Bachelier), 1842. 4to. No wrappers. In: ""Comptes Rendus Hebdomadaires des Séances de L'Academie des Sciences"", Tome 14, No. 10. Pp. (349-) 378. (Entire issue offered). Donné's paper: pp. 366-368.
First printing of the paper, announcing the discovery of blood-platelets, THE THIRD CORPUSCLES OF THE BLOOD. Platelets, or thrombocytes or yellow blood cells, are very small, irregularly shaped clear cell fragments (i.e. cells that do not have a nucleus containing DNA), 2-3 µm in diameter, which derive from fragmentation of precursor megakaryocytes. The average lifespan of a platelet is normally just 5 to 9 days. Platelets are a natural source of growth factors. They circulate in the blood of mammals and are involved in hemostasis, leading to the formation of blood clots. Platelets release thread-like fibers to form these clots.Garrison & Morton, 864.
P., et Londres, Baillière, 1842, in 12 relié demi-basane verte, dos lisse orné de doubles filets dorés, XI-308 pages ; des rousseurs ; infimes frottis.
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Paris Librairie J.B Baillière et fils. 1875 378p 1 volume petit In8. Reliure en demi-chagrin noire. Dos à nerfs orné. Cinquième édition.
AL. DONNE avocat, docteur en médecine de Paris, pour le concours de 1832.
Reference : GF31527
(1830)
1830 Paris, Le Normant, 1832 - Une plaquette in-4 de 34 pages à toutes marges sur papier chiffon. couverture muette verte.
Bon exemplaire,en bon état -