A Paris, chez J.B. Baillière ; A londres chez H. Baillière ; A New-York chez H. Baillière ; A Madrid chez C. Bailly-Baillière, 1853; un volume in 4, broché, couverture muette (postérieure), (quelques rousseurs), 92pp., (1) ---- le feuillet de dédicace IMPRIME qui se trouve généralement après la page de titre manque (The printed dedication leaf is lacking)
Reference : 450
---- Edition en librairie de la très rare thèse de Claude Bernard publiée la même année que l'édition originale ---- Horblit 11a : " Remarkable exposition of the glycogenic function of the liver" ---- Norman N° 200 : "First monograph edition. Bernard's treatise, which he used to obtain his doctorate in science, disproved two current theories of animal metabolism : first, that animals cannot synthesize sugar ; and second, that sugar in the blood only occurs in diabetic or otherwise unhealthy animals. Bernard devised a series of experiments in which healthy animals were fed either starchy or meat diets, or in some cases not fed at all for several days. He found sugar in the blood of all the animals he examined, even in those from which food had been withheld, which led him to conclude that glycemia is a normal and constant metabolic process independent of food intake, and that blood sugar must thus be produced by a source within the animal body. Upon further experimentation, he identified this source as the liver, demonstrating that it produces sugar and empties it into the blood... The thesis was published the same year by L. Martinet..."**450(7572)/D2
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