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"PIRIA, RAFFAELE. - THE DISCOVERY OF SALICIN - ASPIRIN.
Recherches sur la Salicine et les produits qui en dérivent.
Paris, Bachelier, 1839. 4to. No wrappers. In: ""Comptes Rendus Hebdomadaires des Séances de L'Academie des Sciences"", Tome VIII, No 13. Pp. (459-) 504. (Entire issue offered). Piria's paper: pp. 479-485.
Reference : 47232
First apperance of a main paper in pharmacology, describing the discovery of Salicylic acid compound, giving it the empirical formula C7H6O3. It is the most successful drug in history. A trillion tablets are consumed every year. Used to treat everything from headaches to heart disease, from rheumatism to cancer - scientists are still struggling to understand all its qualities. But aspirin can truly claim the title of wonder drug.Raffaele Piria (20 August 1814 - 18 July 1865), an Italian chemist from Scilla who converted the substance Salicin into a sugar and a second component, which on oxidation becomes salicylic acid, a major component of an analgesic drug, Aspirin (acetylsalicylic acid).Garrison & Morton No 1857.
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2 book(s) with the same title
PIRIA, R. (RAFFAELE). - THE FIRST PREPARATION OF SALICYLIC ACID THE MAIN COMPONENT OF ASPIRIN.
Reference : 45623
(1838)
Recherches sur la Salicine et les Produits qui en dérivent.
(Paris, Crochard et Comp., 1838). No wrappers. In 'Annales de Chimie et de Physique', 2e series, Volume 69, third- issue, pp. 225-352 (entire issue offered). Piria's paper: pp. 281-325.
First appearance of the paper in which Piria relates how he for the first time prepared Salicylic Acid in its pure state. Salicylic acid occurs naturally in the bark of plants such as willow trees and is used to create aspirin and skin care products. Salicylic acid, whether used internally or externally, is associated with some potential hazards. Henri Leroux had extracted salicin, in crystalline form for the first time, but Piria was the first to extract its pure form.Garrison & Morton: No 1857 (referring to the same paper published a year later in Comptes Rendues).
